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No Sweat: Research Suggests Anhidrosis Might Be Heritable Situation – Horse Racing Information

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by Paulick Report Employees|07.22.202307.21.2023|9:51am6:07pm

A horse that can’t sweat in any respect or that does not sweat sufficient is affected by a situation known as anhidrosis. This situation happens extra incessantly in some breeds and amongst horses with a familial historical past of the illness.

The lack to sweat is a welfare concern because the horse is usually not in a position to cool itself successfully in scorching and humid environments. Analysis out of the College of Florida means that there could also be a heritable element to the illness.

Drs. Samantha Brooks and Laura Patterson Rosa used the Genome-Extensive Affiliation Research (GWAS) to search for genomic associations with anhidrosis. Utilizing data from 200 horses, they found a strongly supported candidate area containing the KCNE4 gene.

Sequence evaluation confirmed a single variation on the gene that encodes a portion of a potassium channel protein with attainable sweat gland outflow might alter KCNE4 perform.

This analysis suggests that there’s some heritability to the situation, although many extra research are wanted to find out whether or not breeding a mare with anhidrosis to a stallion that does not have the situation would “cancel out” the anhidrosis susceptibility.

Learn extra at EQUUS magazine.

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